Monotherapy or in combination w/ sulfonylurea for maturity onset DM not responsive to diet.
Dosage/Direction for Use
Initially 500 mg tds or 850 mg bd, gradually increased if necessary to max: 3 g daily.
Administration
Should be taken with food.
Contraindications
CV collapse, CHF, acute MI, or other conditions leading to hypotension or hypoxaemia. DM complicated by acidosis, infection or gangrene. Surgery. Hepatic or renal impairment. Pregnancy.
Special Precautions
Lactic acidosis. Discontinue therapy prior to surgery & administration w/ iodinated contrast agent. Renal impairment. Lactation. Childn <12 yr.
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